Could pyrrole disorders be holding back your health? Pyrroluria is a condition in which the the body produces excess of pyrroles. Pyrroles are normally produced in small numbers as a byproduct of hemoglobin synthesis and excreted in the urine. However, some people produce an abnormally large numbers of pyrroles. These pyrroles then bind to pyridoxine (B6) and zinc, causing them to be excreted from the body, with deficiency states arising as a result.
Pyrroluria creates wide range of symptoms – physical, mental and emotional – but is particularly associated with emotional and psychiatric issues eg autism, ADHD, behavioral issues, depression, anxiety, aggressive behavior, schizophrenia. Physical symptoms include poor digestion, poor appetite especially in the morning, low tolerance for protein, white flecks on the fingernails, tooth and gum problems, motion sickness, allergies and fatigue.